Individual patient response to amphetamines varies widely: toxic symptoms can occur at doses as low as 2 mg but are rare with doses of less than 15 mg 30 mg can produce severe reactions yet doses of 400 to 500 mg are not necessarily fatal.Drug tablets contain d-amphetamine and l-amphetamine salts in a 3:1 ratio.This drug should be stored between 20 to 25 degrees Celsius (68 to 77 Fahrenheit) and dispensed in a tight, light-resistant container.The dose of a single XR capsule should not be divided.XR capsules may be taken whole or capsule contents may be sprinkled on applesauce the applesauce mixture should be consumed immediately without chewing.This drug can be taken with or without food.Late evening doses should be avoided because of the potential for insomnia afternoon doses also should be avoided if taking the XR formulation.Regardless of indication, this drug should be administered at the lowest effective dose dosage should be individualized according to patient needs and responses.Patients taking divided doses (e.g., 2 times a day) of the IR formulation may be switched to the XR formulation at the same total daily dose taken once a day.US Controlled Substance: Schedule II Dialysis For narcolepsy treatment, the IR formulation is not recommended in children younger than 6 years the XR formulation is not indicated to treat this condition in children.Ĭonsult WARNINGS section for additional precautions.For ADHD treatment, the IR formulation is not recommended in children younger than 3 years and the XR formulation is not recommended in children younger than 6 years.Long-term effects of amphetamines in children have not been well established. Drug misuse may cause sudden death and serious cardiovascular adverse events.Administering this drug for prolonged periods of time should be avoided as it may lead to drug dependence.Due to the high abuse potential, this drug should be prescribed/dispensed sparingly and particular attention should be paid to subjects possibly obtaining this drug for non-therapeutic use or distribution to others.Use: Narcolepsy treatment Renal Dose Adjustmentsĭata not available Liver Dose Adjustments Narcolepsy rarely occurs in children under 12 years of age.Initial Dose: 5 mg orally per day in divided doses.Use: As part of a total treatment program for Attention Deficit Hyperactivity Disorder (ADHD). IR: The first dose should be given on awakening 1 to 2 additional doses should be given at intervals of 4 to 6 hours.Maintenance Dose: Daily dose may be increased to 20 mg/day after one week if symptoms are not adequately controlled.Maintenance Dose: Daily dose may be raised in 5 to 10 mg increments at weekly intervals.Īge 13 to 17 Years (starting treatment for the first time or switching from another medication):.Initial Dose: 5 or 10 mg orally once a day in the morning.Maintenance Dose: Daily dose may be raised in 2.5 mg increments at weekly intervals until optimal response is obtained.Īge 6 to 12 Years (starting treatment for the first time or switching from another medication):.Use: Narcolepsy treatment Usual Pediatric Dose for Attention Deficit Disorder
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